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The Variability of the Harlequin Mouse Phenotype Resembles that of Human Mitochondrial-Complex I-Deficiency Syndromes

BACKGROUND: Despite the considerable progress made in understanding the molecular bases of mitochondrial diseases, no effective treatments have been developed to date. Faithful animal models would be extremely helpful for designing such treatments. We showed previously that the Harlequin mouse pheno...

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Main Authors: Bénit, Paule, Goncalves, Sergio, Dassa, Emmanuel Philippe, Brière, Jean-Jacques, Rustin, Pierre
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527683/
https://ncbi.nlm.nih.gov/pubmed/18791645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003208
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