Novel Mediators of Amyloid Precursor Protein Signaling

Multiple recent reports implicate amyloid precursor protein (APP) signaling in the pathogenesis of Alzheimer's disease, but the APP-dependent signaling network involved has not been defined. Here, we report a novel consensus sequence for interaction with the PDZ-1 and PDZ-2 domains of the APP-i...

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Detalhes bibliográficos
Main Authors: Swistowski, Andrzej, Zhang, Qiang, Orcholski, Mark E., Crippen, Danielle, Vitelli, Cathy, Kurakin, Alexei, Bredesen, Dale E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823633/
https://ncbi.nlm.nih.gov/pubmed/20016085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4351-09.2009
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