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Calmodulin Wraps around Its Binding Domain in the Plasma Membrane Ca(2+) Pump Anchored by a Novel 18-1 Motif
Using solution NMR spectroscopy, we obtained the structure of Ca(2+)-calmodulin (holoCaM) in complex with peptide C28 from the binding domain of the plasma membrane Ca(2+)-ATPase (PMCA) pump isoform 4b. This provides the first atomic resolution insight into the binding mode of holoCaM to the full-le...
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Main Authors: | , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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American Society for Biochemistry and Molecular Biology
2010
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823543/ https://ncbi.nlm.nih.gov/pubmed/19996092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.060491 |
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