Determinants for the Rhesus Monkey TRIM5α-mediated Block of the Late Phase of HIV-1 Replication

Rhesus monkey TRIM5α (TRIM5αrh) includes RING, B-box, coiled-coil, and B30.2(PRYSPRY) domains and blocks HIV-1 infection by targeting HIV-1 core through a B30.2(PRYSPRY) domain. Previously, we reported that TRIM5αrh also blocks HIV-1 production in a B30.2(PRYSPRY)-independent manner. Efficient encap...

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Bibliographic Details
Main Authors: Sakuma, Ryuta, Ohmine, Seiga, Ikeda, Yasuhiro
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823520/
https://ncbi.nlm.nih.gov/pubmed/19951947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.059063
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