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Alpha Interferon Enhances TRIM5α-Mediated Antiviral Activities in Human and Rhesus Monkey Cells

Dominant, constitutively expressed antiretroviral factors, including TRIM5α and APOBEC3 proteins, are distinguished from the conventional innate immune systems and are classified as intrinsic immunity factors. Here, we demonstrate that interferon alpha (IFN-α) treatment upregulates TRIM5α mRNA in rh...

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Detalhes bibliográficos
Main Authors: Sakuma, Ryuta, Mael, Amber A., Ikeda, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045407/
https://ncbi.nlm.nih.gov/pubmed/17609277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00419-07
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