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Heparin Enhances Serpin Inhibition of the Cysteine Protease Cathepsin L
The glycosaminoglycan heparin is known to possess antimetastatic activity in experimental models and preclinical studies, but there is still uncertainty over its mechanism of action in this respect. As an anticoagulant, heparin enhances inhibition of thrombin by the serpin antithrombin III, but a si...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823513/ https://ncbi.nlm.nih.gov/pubmed/19959474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.037358 |
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