Lipopolysaccharides Up-regulate Kir6.1/SUR2B Channel Expression and Enhance Vascular K(ATP) Channel Activity via NF-κB-dependent Signaling

Sepsis is a severe medical condition causing a large number of deaths worldwide. Recent studies indicate that the septic susceptibility is attributable to the vascular ATP-sensitive K(+) (K(ATP)) channel. However, the mechanisms underlying the channel modulation in sepsis are still unclear. Here we...

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Detalhes bibliográficos
Main Authors: Shi, Weiwei, Cui, Ningren, Wu, Zhongying, Yang, Yang, Zhang, Shuang, Gai, Hongyu, Zhu, Daling, Jiang, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823456/
https://ncbi.nlm.nih.gov/pubmed/19959479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.058313
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