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The Conformational Transition Pathway of ATP Binding Cassette Transporter MsbA Revealed by Atomistic Simulations

ATP binding cassette transporters are integral membrane proteins that use the energy released from ATP hydrolysis at the two nucleotide binding domains (NBDs) to translocate a wide variety of substrates through a channel at the two transmembrane domains (TMDs) across the cell membranes. MsbA from Gr...

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Autori principali: Weng, Jing-Wei, Fan, Kang-Nian, Wang, Wen-Ning
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823423/
https://ncbi.nlm.nih.gov/pubmed/19996093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056432
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