Cysteine Mutagenesis Reveals Transmembrane Residues Associated with Charge Translocation in Prestin

The solute carrier transmembrane protein prestin (SLC26A5) drives an active electromechanical transduction process in cochlear outer hair cells that increases hearing sensitivity and frequency discrimination in mammals. A large intramembraneous charge movement, the nonlinear capacitance (NLC), is th...

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Hlavní autoři: McGuire, Ryan M., Liu, Haiying, Pereira, Fred A., Raphael, Robert M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Membrane Transport, Structure, Function, and Biogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823402/
https://ncbi.nlm.nih.gov/pubmed/19926791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053249
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