Cysteine Mutagenesis Reveals Transmembrane Residues Associated with Charge Translocation in Prestin

The solute carrier transmembrane protein prestin (SLC26A5) drives an active electromechanical transduction process in cochlear outer hair cells that increases hearing sensitivity and frequency discrimination in mammals. A large intramembraneous charge movement, the nonlinear capacitance (NLC), is th...

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Bibliographische Detailangaben
Hauptverfasser: McGuire, Ryan M., Liu, Haiying, Pereira, Fred A., Raphael, Robert M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Membrane Transport, Structure, Function, and Biogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823402/
https://ncbi.nlm.nih.gov/pubmed/19926791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053249
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