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PU.1 Directly Regulates cdk6 Gene Expression, Linking the Cell Proliferation and Differentiation Programs in Erythroid Cells

Cell proliferation and differentiation are highly coordinated processes during normal development. Most leukemia cells are blocked from undergoing terminal differentiation and also exhibit uncontrolled proliferation. Dysregulated expression of transcription factor PU.1 is strongly associated with Fr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Choe, Kevin S., Ujhelly, Olga, Wontakal, Sandeep N., Skoultchi, Arthur I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823399/
https://ncbi.nlm.nih.gov/pubmed/19955566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077727
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