The Neuronal MicroRNA miR-326 Acts in a Feedback Loop with Notch and Has Therapeutic Potential against Brain Tumors

Little is known of microRNA interactions with cellular pathways. Few reports have associated microRNAs with the Notch pathway, which plays key roles in nervous system development and in brain tumors. We previously implicated the Notch pathway in gliomas, the most common and aggressive brain tumors....

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Hlavní autoři: Kefas, Benjamin, Comeau, Laurey, Floyd, Desiree H., Seleverstov, Oleksandr, Godlewski, Jakub, Schmittgen, Tom, Jiang, Jinmai, diPierro, Charles G., Li, Yunqing, Chiocca, E. Antonio, Lee, Jeongwu, Fine, Howard, Abounader, Roger, Lawler, Sean, Purow, Benjamin
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823067/
https://ncbi.nlm.nih.gov/pubmed/19955368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4966-09.2009
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