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Notch-1 regulates transcription of the epidermal growth factor receptor through p53
The Notch pathway plays a key role in the development and is increasingly recognized for its importance in cancer. We demonstrated previously the overexpression of Notch-1 and its ligands in gliomas and showed that their knockdown inhibits glioma cell proliferation and survival. To elucidate the mec...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902388/ https://ncbi.nlm.nih.gov/pubmed/18359760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn079 |
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