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Defects in DNA Lesion Bypass Lead to Spontaneous Chromosomal Rearrangements and Increased Cell Death

Rev3 polymerase and Mph1 DNA helicase participate in error-prone and error-free pathways, respectively, for the bypassing of template lesions during DNA replication. Here we have investigated the role of these pathways and their genetic interaction with recombination factors, other nonreplicative DN...

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Bibliografski detalji
Glavni autori: Schmidt, Kristina H., Viebranz, Emilie B., Harris, Lorena B., Mirzaei-Souderjani, Hamed, Syed, Salahuddin, Medicus, Robin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823012/
https://ncbi.nlm.nih.gov/pubmed/20008080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00260-09
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