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Defects in DNA Lesion Bypass Lead to Spontaneous Chromosomal Rearrangements and Increased Cell Death

Rev3 polymerase and Mph1 DNA helicase participate in error-prone and error-free pathways, respectively, for the bypassing of template lesions during DNA replication. Here we have investigated the role of these pathways and their genetic interaction with recombination factors, other nonreplicative DN...

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Detalhes bibliográficos
Main Authors: Schmidt, Kristina H., Viebranz, Emilie B., Harris, Lorena B., Mirzaei-Souderjani, Hamed, Syed, Salahuddin, Medicus, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823012/
https://ncbi.nlm.nih.gov/pubmed/20008080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00260-09
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