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Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants

Saccharomyces cerevisiae mutants lacking two of the three DNA helicases Sgs1, Srs2, and Rrm3 exhibit slow growth that is suppressed by disrupting homologous recombination. Cells lacking Sgs1 and Rrm3 accumulate gross-chromosomal rearrangements (GCRs) that are suppressed by the DNA damage checkpoint...

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Autors principals: Schmidt, Kristina H., Kolodner, Richard D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838729/
https://ncbi.nlm.nih.gov/pubmed/17114288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608566103
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