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Arylhydrocarbon Receptor Activation in NCI-H441 Cells and C57BL/6 Mice: Possible Mechanisms for Lung Dysfunction

The arylhydrocarbon receptor (AhR) is known for its ability to bind aromatic-containing compounds, which starts a molecular cascade involving the induction of cytochrome P450s and inflammatory cytokines. Our hypothesis is that many inhaled environmental toxicant components activate these inflammator...

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Autors principals: Wong, Patrick S., Vogel, Chris F., Kokosinski, Katherine, Matsumura, Fumio
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822982/
https://ncbi.nlm.nih.gov/pubmed/19372248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0228OC
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