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Arylhydrocarbon Receptor Activation in NCI-H441 Cells and C57BL/6 Mice: Possible Mechanisms for Lung Dysfunction
The arylhydrocarbon receptor (AhR) is known for its ability to bind aromatic-containing compounds, which starts a molecular cascade involving the induction of cytochrome P450s and inflammatory cytokines. Our hypothesis is that many inhaled environmental toxicant components activate these inflammator...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Thoracic Society
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822982/ https://ncbi.nlm.nih.gov/pubmed/19372248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0228OC |
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