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Arylhydrocarbon Receptor Activation in NCI-H441 Cells and C57BL/6 Mice: Possible Mechanisms for Lung Dysfunction
The arylhydrocarbon receptor (AhR) is known for its ability to bind aromatic-containing compounds, which starts a molecular cascade involving the induction of cytochrome P450s and inflammatory cytokines. Our hypothesis is that many inhaled environmental toxicant components activate these inflammator...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Thoracic Society
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822982/ https://ncbi.nlm.nih.gov/pubmed/19372248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0228OC |
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