Mixed S-Nitrosylated Polymerized Bovine Hemoglobin Species Moderate Hemodynamic Effects in Acutely Hypoxic Rats

Hemoglobin (Hb)-based oxygen carriers (HBOCs) are being developed as a potential therapy for increasing tissue oxygenation, yet they have not reached their full potential because of unwanted hemodynamic side effects (vasoconstriction, low cardiac output, and oxygen delivery) due in part to nitric ox...

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Main Authors: Irwin, David, Buehler, Paul W., Alayash, Abdu I., Jia, Yiping, Bonventura, Joe, Foreman, Ben, White, Molly, Jacobs, Robert, Piteo, Brian, TissotvanPatot, Martha C., Hamilton, Karyn L., Gotshall, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2010
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822981/
https://ncbi.nlm.nih.gov/pubmed/19395680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0364OC
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