Glutaraldehyde-polymerized bovine hemoglobin and phosphodiesterase-5 inhibition

OBJECTIVE: Hemoglobin-based oxygen carriers (HBOC) of several types scavenge nitric oxide from the vasculature resulting in vasoconstriction and hypertension, both systemic and pulmonary. Phosphodiesterase-5 (PDE5) inhibitors promote nitric oxide activity and enhance vasodilation. The purpose of thi...

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Hlavní autoři: Gotshall, Robert W., Hamilton, Karyn L., Foreman, Benjamin, Tissot van Patot, Martha C., Irwin, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816936/
https://ncbi.nlm.nih.gov/pubmed/19384199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3181a00597
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