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Glutaraldehyde-polymerized bovine hemoglobin and phosphodiesterase-5 inhibition
OBJECTIVE: Hemoglobin-based oxygen carriers (HBOC) of several types scavenge nitric oxide from the vasculature resulting in vasoconstriction and hypertension, both systemic and pulmonary. Phosphodiesterase-5 (PDE5) inhibitors promote nitric oxide activity and enhance vasodilation. The purpose of thi...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816936/ https://ncbi.nlm.nih.gov/pubmed/19384199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3181a00597 |
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