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Statistical method on nonrandom clustering with application to somatic mutations in cancer
BACKGROUND: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a consequence of genomic instability and high levels of proliferation, many passenger mutations that do not contribute to the ca...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822753/ https://ncbi.nlm.nih.gov/pubmed/20053295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-11 |
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