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CRF(1) receptor activation mediates nicotine withdrawal-induced deficit in brain reward function and stress-induced relapse

BACKGROUND: Tobacco addiction is a chronic brain disorder that is characterized by a negative affective state upon smoking cessation and relapse after periods of abstinence. Previous research has shown that blockade of CRF receptors with a non-specific CRF(1)/CRF(2) receptor antagonist prevents the...

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Autors principals: Bruijnzeel, Adrie W., Prado, Melissa, Isaac, Shani
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822665/
https://ncbi.nlm.nih.gov/pubmed/19217073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.01.010
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