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CRF(1) receptor activation mediates nicotine withdrawal-induced deficit in brain reward function and stress-induced relapse
BACKGROUND: Tobacco addiction is a chronic brain disorder that is characterized by a negative affective state upon smoking cessation and relapse after periods of abstinence. Previous research has shown that blockade of CRF receptors with a non-specific CRF(1)/CRF(2) receptor antagonist prevents the...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822665/ https://ncbi.nlm.nih.gov/pubmed/19217073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.01.010 |
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