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Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling
The primary biological function of the endogenous cellular prion protein has remained unclear. We investigated its biological function in the generation of cellular immune responses using cellular prion protein gene-specific small interfering ribonucleic acid in vivo and in vitro. Our results were c...
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Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Oxford University Press
2010
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822628/ https://ncbi.nlm.nih.gov/pubmed/20145049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp298 |
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