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IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
During T cell–dependent responses, B cells can either differentiate extrafollicularly into short-lived plasma cells or enter follicles to form germinal centers (GCs). Interactions with T follicular helper (Tfh) cells are required for GC formation and for selection of somatically mutated GC B cells....
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822609/ https://ncbi.nlm.nih.gov/pubmed/20142429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091738 |
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