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Low-dose sodium nitrite vasodilates hypoxic human pulmonary vasculature by a means that is not dependent on a simultaneous elevation in plasma nitrite

Inorganic nitrite has recently been recognized to possess vascular activity that is enhanced in hypoxia. This has been demonstrated in humans in the forearm vascular bed. In animal models nitrite reduces pulmonary vascular resistance, but its effects upon the pulmonary circulation of humans have not...

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Bibliographic Details
Main Authors: Ingram, Thomas E., Pinder, Andrew G., Bailey, Damian M., Fraser, Alan G., James, Philip E.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822592/
https://ncbi.nlm.nih.gov/pubmed/19940079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00583.2009
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