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Mechanisms of chromosomal rearrangement in the human genome

Many human cancers are associated with characteristic chromosomal rearrangements, especially hematopoietic cancers such as leukemias and lymphomas. The first and most critical step in the rearrangement process is the induction of two DNA double-strand breaks (DSB). In all cases, at least one of the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tsai, Albert G, Lieber, Michael R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822523/
https://ncbi.nlm.nih.gov/pubmed/20158866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-S1-S1
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