Mechanisms of transcriptional modulation of the human anion exchanger SLC26A3 gene expression by IFN-γ

Two members of the SLC26 gene family, SLC26A3 or DRA (downregulated in adenoma) and SLC26A6 (putative anion transporter 1, PAT1), are known to play a major role in apical Cl(−)/OH(−) (HCO(3)(−)) exchange process in the human intestine. We have previously shown the inhibitory effects of IFN-γ (30 ng/...

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Detalhes bibliográficos
Main Authors: Saksena, Seema, Singla, Amika, Goyal, Sonia, Katyal, Shivani, Bansal, Nikhil, Gill, Ravinder K., Alrefai, Waddah A., Ramaswamy, Krishnamurthy, Dudeja, Pradeep K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Inflammation/Immunity/Mediators
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822505/
https://ncbi.nlm.nih.gov/pubmed/19940027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00374.2009
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