A kisspeptin-10 analog with greater in vivo bioactivity than kisspeptin-10

The kisspeptins are neuropeptides that stimulate the hypothalamo-pituitary-gonadal (HPG) axis. The smallest endogenous kisspeptin, kisspeptin-10 (KP-10), binds to the receptor KISS1R with a similar affinity to the full-length peptide, kisspeptin-54 (KP-54), but is less effective in vivo, possibly be...

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Auteurs principaux: Curtis, Annette E., Cooke, Jennifer H., Baxter, Jordan E., Parkinson, James R. C., Bataveljic, Attia, Ghatei, Mohammad A., Bloom, Stephen R., Murphy, Kevin G.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2010
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822479/
https://ncbi.nlm.nih.gov/pubmed/19934405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00426.2009
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