Kisspeptin-54 at high doses acutely induces testicular degeneration in adult male rats via central mechanisms

BACKGROUND AND PURPOSE: The kisspeptins are critical regulators of reproduction and a therapeutic target for reproductive disease. Intracerebroventricular (i.c.v.) or peripheral injection of kisspeptin potently stimulates the hypothalamic-pituitary gonadal (HPG) axis via gonadotrophin-releasing horm...

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Detalhes bibliográficos
Main Authors: Thompson, EL, Amber, V, Stamp, GWH, Patterson, M, Curtis, AE, Cooke, JH, Appleby, GF, Dhillo, WS, Ghatei, MA, Bloom, SR, Murphy, KG
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697701/
https://ncbi.nlm.nih.gov/pubmed/19226253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00061.x
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