Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization

BACKGROUND. Patients with mutations that inactivate kisspeptin signaling are infertile. Kisspeptin-54, the major circulating isoform of kisspeptin in humans, potently stimulates reproductive hormone secretion in humans. Animal studies suggest that kisspeptin is involved in generation of the luteiniz...

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Autori principali: Jayasena, Channa N., Abbara, Ali, Comninos, Alexander N., Nijher, Gurjinder M.K., Christopoulos, Georgios, Narayanaswamy, Shakunthala, Izzi-Engbeaya, Chioma, Sridharan, Mathini, Mason, Alexina J., Warwick, Jane, Ashby, Deborah, Ghatei, Mohammad A., Bloom, Stephen R., Carby, Anna, Trew, Geoffrey H., Dhillo, Waljit S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2014
Soggetti:
Clinical Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109525/
https://ncbi.nlm.nih.gov/pubmed/25036713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75730
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