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Bioactivity of Analogs of the N-Terminal Region of Gastrin-17

Gastrin-17-Gly (G17-Gly) has been shown to bind to non-CCK nanomolar and micromolar affinity sites on DLD-1 and HT-29 human colonic carcinoma cells and to stimulate cellular proliferation. However, in previous studies, we showed that C-terminal truncation of the gastrin-17 (G17) to the G17 analog G1...

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Hlavní autoři: Copps, Jeffrey, Ahmed, Shawn, Murphy, Richard F., Lovas, Sándor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787808/
https://ncbi.nlm.nih.gov/pubmed/19761808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2009.09.012
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