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The Effects of C-terminal Modifications on the Opioid Activity of [N-BenzylTyr(1)]Dynorphin A-(1-11) Analogs

Structural modifications affecting the efficacy of analogs of the endogenous opioid peptide dynorphin (Dyn) A have focused on the N-terminal “message” sequence, based on the “message-address” concept. To test the hypothesis that changes in the C-terminal “address” domain could affect efficacy, modif...

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書誌詳細
主要な著者: Patkar, Kshitij A., Murray, Thomas F., Aldrich, Jane V.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416884/
https://ncbi.nlm.nih.gov/pubmed/19807094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900715m
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