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Genetic determinants of neoplastic transformation by the retroviral oncogene v-erbB.

The retroviral oncogene v-erbB is a mutant version of the gene (c-erbB or ERBB1) that encodes the cell-surface epidermal growth factor receptor (EGFR). The mutations take three forms: (i) a large deletion that removes the entire ligand-binding domain of EGFR, (ii) smaller deletions that affect the c...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wells, A, Bishop, J M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282239/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2902633/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.20.7597
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