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Genetic determinants of neoplastic transformation by the retroviral oncogene v-erbB.

The retroviral oncogene v-erbB is a mutant version of the gene (c-erbB or ERBB1) that encodes the cell-surface epidermal growth factor receptor (EGFR). The mutations take three forms: (i) a large deletion that removes the entire ligand-binding domain of EGFR, (ii) smaller deletions that affect the c...

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Autors principals: Wells, A, Bishop, J M
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC282239/
https://ncbi.nlm.nih.gov/pubmed/2902633
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