Genetic determinants of neoplastic transformation by the retroviral oncogene v-erbB.
The retroviral oncogene v-erbB is a mutant version of the gene (c-erbB or ERBB1) that encodes the cell-surface epidermal growth factor receptor (EGFR). The mutations take three forms: (i) a large deletion that removes the entire ligand-binding domain of EGFR, (ii) smaller deletions that affect the c...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1988
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282239/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2902633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.20.7597 |
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