A rapid and sensitive method for determination of veliparib (ABT-888) in human plasma, bone marrow cells and supernatant by using LC/MS/MS

A rapid and sensitive method was developed and validated using a liquid chromatographic method with tandem mass spectrometry detection (LC/MS/MS) for determination of veliparib (ABT-888) in plasma, bone marrow supernatant, and bone marrow cells. Sample preparation involved a single protein precipita...

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Detalhes bibliográficos
Main Authors: Reinhardt, Sarah, Zhao, Ming, Mnatsakanyan, Aleksander, Xu, Linping, Ricklis, Rebecca M., Chen, Alice, Karp, Judith E., Rudek, Michelle A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822340/
https://ncbi.nlm.nih.gov/pubmed/20071126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2009.12.015
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