Detection of Aberrant p16(INK4A) Methylation in Sera of Patients with Liver Cirrhosis and Hepatocellular Carcinoma

Hepatocellular carcinomas (HCCs) show genomic alterations, including DNA rearrangements associated with HBV DNA integration, loss of heterozygosity, and chromosomal amplification. The genes most frequently involved are those encoding tumor suppressors. The p16(INK4A) tumor suppressor gene frequently...

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Bibliographische Detailangaben
Hauptverfasser: Chu, Hyung Jun, Heo, Jeong, Seo, Soo Boon, Kim, Gwang Ha, Kang, Dae Hwan, Song, Geun Am, Cho, Mong, Yang, Ung Suk
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Academy of Medical Sciences 2004
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822270/
https://ncbi.nlm.nih.gov/pubmed/14966347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2004.19.1.83
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