Detection of Aberrant p16(INK4A) Methylation in Sera of Patients with Liver Cirrhosis and Hepatocellular Carcinoma

Hepatocellular carcinomas (HCCs) show genomic alterations, including DNA rearrangements associated with HBV DNA integration, loss of heterozygosity, and chromosomal amplification. The genes most frequently involved are those encoding tumor suppressors. The p16(INK4A) tumor suppressor gene frequently...

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Detalhes bibliográficos
Main Authors: Chu, Hyung Jun, Heo, Jeong, Seo, Soo Boon, Kim, Gwang Ha, Kang, Dae Hwan, Song, Geun Am, Cho, Mong, Yang, Ung Suk
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Medical Sciences 2004
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822270/
https://ncbi.nlm.nih.gov/pubmed/14966347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2004.19.1.83
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