Aberrant p16INK4A methylation: Relation to viral related chronic liver disease and hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is currently the fifth most common solid tumor worldwide and the third leading cause of cancer related deaths. Several studies have shown that the tumor suppressor gene p16INK4A is frequently downregulated by aberrant methylation of the 5’-cytosine-phosphog...

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Main Authors: El-Mougy, Fatma A., Youssef, Mohammed M., Omran, Dalia A., Sharaf, Sahar A., El-Sayed, Hany H., Rabie, Walaa A., Mohamed, Elghobary A., Elghobary, Hany A.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2014
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BENCH-PRESS: Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961859/
https://ncbi.nlm.nih.gov/pubmed/24665436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2278-330X.126498
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