Modulation of Alpha-Synuclein Aggregation by Dopamine Analogs

The action of dopamine on the aggregation of the unstructured alpha-synuclein (α-syn) protein may be linked to the pathogenesis of Parkinson's disease. Dopamine and its oxidation derivatives may inhibit α-syn aggregation by non-covalent binding. Exploiting this fact, we applied an integrated co...

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Bibliographic Details
Main Authors: Latawiec, Diane, Herrera, Fernando, Bek, Alpan, Losasso, Valeria, Candotti, Michela, Benetti, Federico, Carlino, Elvio, Kranjc, Agata, Lazzarino, Marco, Gustincich, Stefano, Carloni, Paolo, Legname, Giuseppe
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821914/
https://ncbi.nlm.nih.gov/pubmed/20169066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009234
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