Effect of 20-HETE inhibition on infarct volume and cerebral blood flow after transient middle cerebral artery occlusion

This study examined the effects of an inhibitor of 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis, N-(3-chloro-4-morpholin-4-yl)phenyl-N′-hydroxyimido formamide (TS-011), on infarct volume, volume at risk, cerebral blood flow (CBF), and levels of cytochrome P450 (CYP450) eicosanoids in the brai...

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Detalhes bibliográficos
Main Authors: Renic, Marija, Klaus, Judith A, Omura, Tomohiro, Kawashima, Naoya, Onishi, Michihito, Miyata, Noriyuki, Koehler, Raymond C, Harder, David R, Roman, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821901/
https://ncbi.nlm.nih.gov/pubmed/19107134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.156
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