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"DAKLI": a multipurpose ligand with high affinity and selectivity for dynorphin (kappa opioid) binding sites.

We describe a synthetic ligand, "DAKLI" (Dynorphin A-analogue Kappa LIgand), related to the opioid peptide dynorphin A. A single reactive amino group at the extended carboxyl terminus permits various reporter groups to be attached, such as 125I-labeled Bolton-Hunter reagent, fluorescein is...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Goldstein, A, Nestor, J J, Naidu, A, Newman, S R
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1988
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282189/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2902630/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7375
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