"DAKLI": a multipurpose ligand with high affinity and selectivity for dynorphin (kappa opioid) binding sites.

We describe a synthetic ligand, "DAKLI" (Dynorphin A-analogue Kappa LIgand), related to the opioid peptide dynorphin A. A single reactive amino group at the extended carboxyl terminus permits various reporter groups to be attached, such as 125I-labeled Bolton-Hunter reagent, fluorescein is...

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Main Authors: Goldstein, A, Nestor, J J, Naidu, A, Newman, S R
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC282189/
https://ncbi.nlm.nih.gov/pubmed/2902630
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