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SLAT/Def6 Plays a Critical Role in the Development of Th17 Cell-Mediated Experimental Autoimmune Encephalomyelitis

SWAP-70-like adapter of T cells (SLAT; also known as Def6) is a novel guanine nucleotide exchange factor for Rho GTPases that has been previously shown to play a role in CD4(+) T cell activation and Th1/Th2 differentiation. However, the role of SLAT/Def6 in autoimmunity and its associated Th1- and T...

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Detalles Bibliográficos
Main Authors: Canonigo-Balancio, Ann J., Fos, Camille, Prod’homme, Thomas, Bécart, Stéphane, Altman, Amnon
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821872/
https://ncbi.nlm.nih.gov/pubmed/19915062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902573
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