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Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization

During apoptosis, the process of mitochondrial outer membrane permeabilization (MOMP) represents a point-of-no-return as it commits the cell to death. Here we have assessed the role of caspases, Bcl-2 family members and the mitochondrial permeability transition pore on ER stress-induced MOMP and sub...

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Detalhes bibliográficos
Main Authors: Gupta, Sanjeev, Cuffe, Lorraine, Szegezdi, Eva, Logue, Susan E., Neary, Catherine, Healy, Sandra, Samali, Afshin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821636/
https://ncbi.nlm.nih.gov/pubmed/20169117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/170215
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