Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization

During apoptosis, the process of mitochondrial outer membrane permeabilization (MOMP) represents a point-of-no-return as it commits the cell to death. Here we have assessed the role of caspases, Bcl-2 family members and the mitochondrial permeability transition pore on ER stress-induced MOMP and sub...

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Détails bibliographiques
Auteurs principaux: Gupta, Sanjeev, Cuffe, Lorraine, Szegezdi, Eva, Logue, Susan E., Neary, Catherine, Healy, Sandra, Samali, Afshin
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821636/
https://ncbi.nlm.nih.gov/pubmed/20169117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/170215
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