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S6 kinase in quiescent Swiss mouse 3T3 cells is activated by phosphorylation in response to serum treatment.

To investigate the role of phosphorylation in the activation of S6 kinase, the enzyme was isolated from 32P-labeled Swiss mouse 3T3 cells before and after stimulation with serum. The kinase activity was followed through several purification steps, and a radioactive protein of Mr 70,000 was obtained...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Ballou, L M, Siegmann, M, Thomas, G
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1988
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845397/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7154
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