Hepatic protein phosphotyrosine phosphatase. Dephosphorylation of insulin and epidermal growth factor receptors in normal and alloxan diabetic rats.

Polypeptide hormone signal transmission by receptor tyrosine kinases requires the rapid reversal of tyrosine phosphorylation by protein phosphotyrosine phosphatases (PPTPases). We studied hepatic PPTPases in the rat with emphasis on acute and chronic regulation by insulin. PPTPase activity with arti...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Gruppuso, P A, Boylan, J M, Posner, B I, Faure, R, Brautigan, D L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296637/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2161429/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114632
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