Hepatic protein phosphotyrosine phosphatase. Dephosphorylation of insulin and epidermal growth factor receptors in normal and alloxan diabetic rats.

Polypeptide hormone signal transmission by receptor tyrosine kinases requires the rapid reversal of tyrosine phosphorylation by protein phosphotyrosine phosphatases (PPTPases). We studied hepatic PPTPases in the rat with emphasis on acute and chronic regulation by insulin. PPTPase activity with arti...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Gruppuso, P A, Boylan, J M, Posner, B I, Faure, R, Brautigan, D L
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296637/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2161429/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114632
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